|Full Name||RNA binding protein S1, serine-rich domain|
|Product Description||Rabbit Polyclonal antibody to RNPS1 (RNA binding protein S1, serine-rich domain)|
|Background||This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq]|
|Synonyms||RNA binding protein S1, serine-rich domain Antibody , E5.1 Antibody|
|Cellular Localization||Nucleus , Nucleus speckle , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human RNPS1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (98%), Chimpanzee (98%), Bovine (100%)|