Full Name | RNA binding protein S1, serine-rich domain |
Background | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq] |
Synonyms | RNA binding protein S1, serine-rich domain Antibody , E5.1 Antibody |
Cellular Localization | Nucleus , Nucleus speckle , Cytoplasm |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human RNPS1. The exact sequence is proprietary. |
Antigen Species | Human |
Species Reactivity | Human |
Predicted Cross Reactivity species Predicted cross-reactivity: Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive. Please note that we are only able to guarantee products to work in applications and species in which they have been tested. | Mouse, Rat, Chimpanzee, Bovine |
Predict Reactivity Note | Mouse (100%), Rat (98%), Chimpanzee (98%), Bovine (100%) |
Conjugation | Unconjugated |