|Full Name||roundabout, axon guidance receptor, homolog 1 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to ROBO1 (roundabout, axon guidance receptor, homolog 1 (Drosophila))|
|Background||Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||DUTT1 antibody, FLJ21882 antibody, MGC131599 antibody, MGC133277 antibody, SAX3 antibody, ROBO1 antibody, roundabout homolog 1 antibody, deleted in U twenty twenty antibody, "roundabout, axon guidance receptor, homolog 1 (Drosophila) antibody"|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human ROBO1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (83%), Bovine (92%)|