| Background | CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq] |
| Synonyms | LY64 antibody, Ly78 antibody, MGC126233 antibody, MGC126234 antibody, RP105 antibody, CD180 antibody, CD180 antigen antibody, "lymphocyte antigen-64, radioprotective, 105kDa antibody", lymphocyte antigen 64 antibody, radioprotective 105 kDa protein antibody, CD180 molecule antibody |