|Full Name||retinitis pigmentosa 2 (X-linked recessive)|
|Product Description||Rabbit Polyclonal antibody to RP2 |
|Background||The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death [provided by RefSeq]|
|Synonyms||XRP2 Antibody , NME10 Antibody , retinitis pigmentosa 2 (X-linked recessive) Antibody , NM23-H10 Antibody , DELXp11.3 Antibody , TBCCD2 Antibody|
|Cellular Localization||Cell membrane; Lipid-anchor; Cytoplasmic side |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RP2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (88%), Rat (87%), Rhesus Monkey (99%), Bovine (94%)|