|Full Name||ribosomal protein L10|
|Product Description||Rabbit polyclonal antibody to RPL10 (ribosomal protein L10)|
|Background||Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L10E family of ribosomal proteins. It is located in the cytoplasm. In vitro studies have shown that the chicken protein can bind to c-Jun and can repress c-Jun-mediated transcriptional activation, but these activities have not been demonstrated in vivo. This gene was initially identified as a candidate for a Wilms tumor suppressor gene, but later studies determined that this gene is not involved in the suppression of Wilms tumor. This gene has been referred to as 'laminin receptor homolog' because a chimeric transcript consisting of sequence from this gene and sequence from the laminin receptor gene was isolated; however, it is not believed that this gene encodes a laminin receptor. Transcript variants utilizing alternative polyA signals exist. The variant with the longest 3' UTR overlaps the deoxyribonuclease I-like 1 gene on the opposite strand. This gene is co-transcribed with the small nucleolar RNA gene U70, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq]|
|Synonyms||DKFZp686J1851 antibody, DXS648 antibody, DXS648E antibody, FLJ23544 antibody, FLJ27072 antibody, NOV antibody, QM antibody, RPL10 antibody, tumor suppressor QM antibody, Wilms tumor-related protein antibody, laminin receptor homolog antibody, 60S ribosomal protein L10 antibody, ribosomal protein L10 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RPL10. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Zebrafish, Drosophila, Pig, Rabbit, Sheep, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (100%), Rat (100%), Zebrafish (92%), Drosophila (80%), Pig (99%), Rabbit (99%), Sheep (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (98%)|