|Full Name||ribosomal protein S3|
|Product Description||Rabbit Polyclonal antibody to RPS3 (ribosomal protein S3)|
|Background||Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq]|
|Synonyms||FLJ26283 antibody, FLJ27450 antibody, MGC87870 antibody, RPS3 antibody, IMR-90 ribosomal protein S3 antibody, 40S ribosomal protein S3 antibody, ribosomal protein S3 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RPS3. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Drosophila, Xenopus laevis, Dog, Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Zebrafish (97%), Drosophila (86%), Xenopus laevis (99%), Dog (99%), Pig (100%), Chicken (98%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|