|Full Name||runt-related transcription factor 1|
|Product Description||Rabbit Polyclonal antibody to RUNX1 (runt-related transcription factor 1)|
|Background||Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||AML1-EVI-1 Antibody , AML1 Antibody , runt-related transcription factor 1 Antibody , EVI-1 Antibody , CBFA2 Antibody , AMLCR1 Antibody , PEBP2aB Antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center of human RUNX1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Xenopus laevis (87%), Pig (98%), Rhesus Monkey (99%), Bovine (98%)|