RbAp46 antibody [N1], N-term
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||48 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||retinoblastoma binding protein 7|
|Product Description||Rabbit Polyclonal antibody to RbAp46 (retinoblastoma binding protein 7)|
|Background||This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. [provided by RefSeq]|
|Synonyms||MGC138867 antibody, MGC138868 antibody, RbAp46 antibody, RBBP7 antibody, histone acetyltransferase type B subunit 2 antibody, histone-binding protein RBBP7 antibody, retinoblastoma-binding protein RbAp46 antibody, G1/S transition control protein-binding protein RbAp46 antibody, retinoblastoma-binding protein 7 antibody, retinoblastoma-binding protein p46 antibody, nucleosome-remodeling factor subunit RBAP46 antibody, RBBP-7 antibody, retinoblastoma binding protein 7 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human RbAp46. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%)|