|Full Name||retinoblastoma binding protein 4|
|Product Description||Rabbit polyclonal antibody to RbAp48 (retinoblastoma binding protein 4)|
|Background||This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||NURF55 antibody, RBAP48 antibody, RBBP4 antibody, CAF-I p48 antibody, CAF-I 48 kDa subunit antibody, RBBP-4 antibody, chromatin assembly factor I p48 subunit antibody, nucleosome-remodeling factor subunit RBAP48 antibody, chromatin assembly factor/CAF-1 p48 subunit antibody, retinoblastoma-binding protein 4 antibody, CAF-1 subunit C antibody, histone-binding protein RBBP4 antibody, retinoblastoma-binding protein p48 antibody, MSI1 protein homolog antibody, chromatin assembly factor 1 subunit C antibody, retinoblastoma binding protein 4 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RbAp48. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Zebrafish (97%), Xenopus laevis (98%), Chicken (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|