|Full Name||UPF2 regulator of nonsense transcripts homolog (yeast)|
|Product Description||Rabbit Polyclonal antibody to Rent2 (regulator of nonsense transcripts 2)|
|Background||This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq]|
|Synonyms||DKFZp434D222 antibody, HUPF2 antibody, KIAA1408 antibody, MGC138834 antibody, MGC138835 antibody, RENT2 antibody, smg-3 antibody, UPF2 antibody, "smg-3 homolog, nonsense mediated mRNA decay factor antibody", regulator of nonsense transcripts 2 antibody, up-frameshift suppressor 2 homolog antibody, nonsense mRNA reducing factor 2 antibody, yeast Upf2p homolog antibody, UPF2 regulator of nonsense transcripts homolog (yeast) antibody|
|Cellular Localization||Cytoplasm , perinuclear region |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Rent2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis|
|Predict Reactivity Note||Rat (100%), Xenopus laevis (100%)|