Rho GDI2 antibody [N1C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||23 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , *mouse fibroblast |
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||Rho GDP dissociation inhibitor (GDI) beta|
|Product Description||Rabbit polyclonal antibody to Rho GDI2 (Rho GDP dissociation inhibitor (GDI) beta)|
|Background||Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM]|
|Synonyms||D4 antibody, GDIA2 antibody, GDID4 antibody, LYGDI antibody, Ly-GDI antibody, RAP1GN1 antibody, RhoGDI2 antibody, ARHGDIB antibody, rho-GDI beta antibody, Rho GDI 2 antibody, rho GDP-dissociation inhibitor 2 antibody, Rho GDP dissociation inhibitor (GDI) beta antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Rho GDI2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Pig, Chicken, Bovine|
|Predict Reactivity Note||Rat (89%), Xenopus laevis (81%), Pig (94%), Chicken (92%), Bovine (93%)|