|Full Name||ras homolog gene family, member C|
|Product Description||Rabbit Polyclonal antibody to RhoC (ras homolog gene family, member C)|
|Background||This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]|
|Synonyms||ARH9 antibody, ARHC antibody, H9 antibody, MGC1448 antibody, MGC61427 antibody, RHOH9 antibody, RHOC antibody, rhoC GTPase antibody, rho-related GTP-binding protein RhoC antibody, rho cDNA clone 9 antibody, RAS-related homolog 9 antibody, small GTP binding protein RhoC antibody, oncogene RHO H9 antibody, ras homolog gene family, member C antibody|
|Cellular Localization||Cell membrane; Lipid-anchor; Cytoplasmic side |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RhoC. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Rat (100%), Xenopus laevis (89%), Chicken (96%), Bovine (100%)|