|Product Description||Rabbit Polyclonal antibody to Rhodopsin (rhodopsin)|
|Background||Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq]|
|Synonyms||rhodopsin Antibody , RHO Antibody , CSNBAD1 Antibody , OPN2 Antibody , RP4 Antibody|
|Cellular Localization||Membrane; Multi-pass membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Rhodopsin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Cat, Pig, Rabbit, Guinea pig|
|Predict Reactivity Note||Dog (100%), Cat (100%), Pig (100%), Rabbit (100%), Guinea pig (100%)|