|Full Name||ribonuclease, RNase A family, 1 (pancreatic)|
|Product Description||Rabbit Polyclonal antibody to Ribonuclease A (ribonuclease, RNase A family, 1 (pancreatic))|
|Background||This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq]|
|Synonyms||MGC12408 antibody, RIB1 antibody, RNS1 antibody, RNASE1 antibody, ribonuclease pancreatic antibody, HP-RNase antibody, RNase 1 antibody, ribonuclease 1 antibody, ribonuclease A antibody, RNase upI-1 antibody, RIB-1 antibody, RNase A antibody, ribonuclease, RNase A family, 1 (pancreatic) antibody|
|Cellular Localization||Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Ribonuclease A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Rhesus Monkey (81%), Chimpanzee (98%)|