|Full Name||ribonuclease/angiogenin inhibitor 1|
|Product Description||Rabbit polyclonal antibody to Ribonuclease Inhibitor (ribonuclease/angiogenin inhibitor 1)|
|Background||Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM]|
|Synonyms||MGC18200 antibody, MGC4569 antibody, MGC54054 antibody, RAI antibody, RNH antibody, RNH1 antibody, placental ribonuclease inhibitor antibody, placental RNase inhibitor antibody, ribonuclease inhibitor antibody, ribonuclease/angiogenin inhibitor 1 antibody|
|Cellular Localization||Cytoplasm |
|Target||Ribonuclease Inhibitor |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Ribonuclease Inhibitor. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%), Chimpanzee (97%)|