|Full Name||stromal antigen 2|
|Product Description||Goat polyclonal antibody to SA2|
|Background||Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. |
|Synonyms||DKFZp686P168, DKFZp781H1753, bA517O1.1, SCC3 homolog 2, FLJ25871, STAG2, SCC3 homolog2, RP11517O1.1, stromal antigen2, stromal antigen 2, SA-2, RP11-517O1.1, SA2, SA 2|
|Cellular Localization||Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. At an|
|Specificity||This antibody is specific for STAG2.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog|