|Full Name||SUMO1 activating enzyme subunit 1|
|Product Description||Rabbit Polyclonal antibody to SAE1 (SUMO1 activating enzyme subunit 1)|
|Background||Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM]|
|Synonyms||AOS1 antibody, FLJ3091 antibody, HSPC140 antibody, SUA1 antibody, UBLE1A antibody, SAE1 antibody, activator of SUMO1 antibody, sentrin/SUMO-activating protein AOS1 antibody, ubiquitin-like protein SUMO-1 activating enzyme antibody, SUMO-activating enzyme subunit 1 antibody, SUMO-1 activating enzyme E1 N subunit antibody, SUMO-1 activating enzyme subunit 1 antibody, ubiquitin-like 1-activating enzyme E1A antibody, SUMO1 activating enzyme subunit 1 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SAE1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (100%), Bovine (98%)|