|Full Name||splicing factor 3a, subunit 2, 66kDa|
|Product Description||Rabbit Polyclonal antibody to SAP62 (splicing factor 3a, subunit 2, 66kDa)|
|Background||This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein. [provided by RefSeq]|
|Synonyms||PRP11 antibody, PRPF11 antibody, SAP62 antibody, SF3a66 antibody, SF3A2 antibody, "pre-mRNA splicing factor SF3A, subunit 2 antibody", SAP 62 antibody, splicing factor 3A subunit 2 antibody, spliceosome associated protein 62 antibody, spliceosome-associated protein 62 antibody, "splicing factor 3a, subunit 2, 66kDa antibody"|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SAP62. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Mouse (99%), Rat (98%), Zebrafish (95%), Xenopus laevis (98%), Chicken (98%), Bovine (99%)|