SART3 antibody [C3], C-term
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||110 kDa (note)
|Positive Controls||A431 , H1299 , HeLa , HepG2 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||squamous cell carcinoma antigen recognized by T cells 3|
|Product Description||Rabbit polyclonal antibody to SART3 (squamous cell carcinoma antigen recognized by T cells 3)|
|Background||The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq]|
|Synonyms||DSAP1 antibody, KIAA0156 antibody, MGC138188 antibody, P100 antibody, RP11-13G14 antibody, TIP110 antibody, p110 antibody, p110(nrb) antibody, SART3 antibody, tat-interacting protein of 110 kDa antibody, squamous cell carcinoma antigen recognized by T-cells 3 antibody, hSART-3 antibody, SART-3 antibody, squamous cell carcinoma antigen recognized by T cells 3 antibody|
|Cellular Localization||Cytoplasm , Nucleus speckle |
|Specificity||Knockdown/Knockout validation was supported by references (PMID:26991000)|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SART3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (100%)|