|Full Name||sterol carrier protein 2|
|Product Description||Rabbit Polyclonal antibody to SCP2 (sterol carrier protein 2)|
|Background||This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq]|
|Synonyms||DKFZp686C12188 antibody, DKFZp686D11188 antibody, NLTP antibody, NSL-TP antibody, SCP-2 antibody, SCP-CHI antibody, SCP-X antibody, SCPX antibody, SCP2 antibody, non-specific lipid-transfer protein antibody, propanoyl-CoA C-acyltransferase antibody, sterol carrier protein X antibody, sterol carrier protein 2 antibody|
|Cellular Localization||Cytoplasm , Mitochondrion , Isoform SCPx: Peroxisome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SCP2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Rabbit|
|Predict Reactivity Note||Mouse (85%), Rat (83%), Pig (81%), Rabbit (87%)|