|Full Name||chemokine (C-X-C motif) ligand 12|
|Product Description||Rabbit Polyclonal antibody to SDF1 (chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1))|
|Background||For background information on chemokines, see CXCL1 (MIM 155730). Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF (see MIM 191160), or IL1 (see MIM 147760). The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.[supplied by OMIM]|
|Synonyms||IRH antibody, PBSF antibody, SCYB12 antibody, SDF1 antibody, SDF1A antibody, SDF1B antibody, TLSF antibody, TPAR1 antibody, CXCL12 antibody, intercrine reduced in hepatomas antibody, pre-B cell growth-stimulating factor antibody, stromal cell-derived factor 1 antibody, chemokine (C-X-C motif) ligand 12 antibody|
|Cellular Localization||Secreted |
|Immunogen||Full length human SDF1 Recombinant protein.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Cat, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (92%), Dog (93%), Cat (95%), Pig (90%), Rhesus Monkey (97%), Bovine (92%)|