|Full Name||sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A|
|Product Description||Rabbit Polyclonal antibody to SEMA3A (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A)|
|Background||This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq]|
|Synonyms||SEMA1 Antibody , COLL1 Antibody , coll-1 Antibody , SEMAD Antibody , SemD Antibody , Hsema-I Antibody , Hsema-III Antibody , SEMAIII Antibody , SEMAL Antibody , sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human SEMA3A. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Xenopus laevis (81%), Chicken (90%), Bovine (98%)|