|Full Name||SUMO1/sentrin/SMT3 specific peptidase 3|
|Product Description||Rabbit Polyclonal antibody to SENP3 (sentrin-specific protease 3)|
|Background||The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM]|
|Synonyms||DKFZp586K0919 antibody, DKFZp762A152 antibody, SMT3IP1 antibody, SSP3 antibody, SENP3 antibody, SUMO-1-specific protease 3 antibody, sentrin-specific protease 3 antibody, sentrin/SUMO-specific protease 3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3 antibody|
|Cellular Localization||Nucleus , nucleolus |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human SENP3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (99%), Xenopus laevis (87%), Chimpanzee (100%), Bovine (100%)|