|Full Name||SUMO1/sentrin specific peptidase 5|
|Product Description||Rabbit Polyclonal antibody to SENP5 (SUMO1/sentrin specific peptidase 5)|
|Background||The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM]|
|Synonyms||DKFZp564O1016 antibody, FLJ42398 antibody, MGC27076 antibody, SENP5 antibody, sentrin/SUMO-specific protease SENP5 antibody, sentrin-specific protease 5 antibody, SUMO1/sentrin specific protease 5 antibody, SUMO1/sentrin specific peptidase 5 antibody|
|Cellular Localization||Nucleus , nucleolus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SENP5. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Xenopus laevis, Rhesus Monkey|
|Predict Reactivity Note||Mouse (97%), Xenopus laevis (81%), Rhesus Monkey (80%)|