|Full Name||SUMO/sentrin specific peptidase family member 8|
|Product Description||Rabbit Polyclonal antibody to SENP8 (SUMO/sentrin specific peptidase family member 8)|
|Background||NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. NEDD8-specific deneddylases, such as NEDP1, or DEN1, are required to process the NEDD8 propeptide at a C-terminal diglycine motif and to remove NEDD8 from cullins (Gan-Erdene et al., 2003 [PubMed 12759363]).[supplied by OMIM]|
|Synonyms||DEN1 antibody, NEDP1 antibody, PRSC2 antibody, SENP8 antibody, sentrin-specific protease 8 antibody, "protease, cysteine 2 antibody", SUMO sentrin specific protease family member 8 antibody, NEDD8 specific-protease cysteine 2 antibody, deneddylase 1 antibody, deneddylase-1 antibody, NEDD8-specific protease 1 antibody, SUMO/sentrin specific peptidase family member 8 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SENP8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey|
|Predict Reactivity Note||Mouse (91%), Rat (92%), Rhesus Monkey (97%)|