SEPT7 antibody [N3C3]
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||51 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||septin 7|
|Product Description||Rabbit Polyclonal antibody to SEPT7 (septin 7)|
|Background||This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. Although the exact function of this gene has not yet been determined, its high similarity to yeast CDC10 and the high conservative nature of eukaryotic cell cycle machinery suggest a similar role to that of its yeast counterpart. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||CDC10 antibody, CDC3 antibody, Nbla02942 antibody, SEPT7A antibody, SEPT7 antibody, "CDC10 (cell division cycle 10, S. cerevisiae, homolog) antibody", septin-7 antibody, CDC10 protein homolog antibody, septin 7 antibody|
|Cellular Localization||Cytoplasm , Kinetochore , Spindle |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SEPT7. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (99%), Rat (99%), Xenopus laevis (98%), Chicken (99%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (100%)|