|Full Name||SET domain, bifurcated 2|
|Product Description||Rabbit Polyclonal antibody to SETDB2 (SET domain, bifurcated 2)|
|Background||Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).[supplied by OMIM]|
|Synonyms||C13orf4 antibody, CLLD8 antibody, CLLL8 antibody, DKFZp586I0123 antibody, DKFZp761J1217 antibody, KMT1F antibody, SETDB2 antibody, histone-lysine N-methyltransferase SETDB2 antibody, chronic lymphocytic leukemia deletion region gene 8 protein antibody, lysine N-methyltransferase 1F antibody, chronic lymphocytic leukemia deletion region 8 antibody, "SET domain, bifurcated 2 antibody"|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SETDB2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (100%), Bovine (92%)|