|Full Name||serine/arginine-rich splicing factor 1|
|Product Description||Rabbit Polyclonal antibody to SF2 (serine/arginine-rich splicing factor 1)|
|Background||This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||ASF antibody, FLJ53078 antibody, MGC5228 antibody, SF2 antibody, SF2p33 antibody, SFRS1 antibody, SRp30a antibody, SRSF1 antibody, SR splicing factor 1 antibody, serine/arginine-rich splicing factor 1 antibody, splicing factor 2 antibody, ASF-1 antibody, alternative-splicing factor 1 antibody, pre-mRNA-splicing factor SF2, P33 subunit antibody, splicing factor, arginine/serine-rich 1 antibody|
|Cellular Localization||Cytoplasm , Nucleus speckle |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SF2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (100%), Pig (100%), Chicken (98%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|