|Full Name||splicing factor 3b, subunit 4, 49kDa|
|Product Description||Rabbit Polyclonal antibody to SF3B4 (splicing factor 3B subunit 4)|
|Background||This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq]|
|Synonyms||Hsh49 antibody, MGC10828 antibody, SAP49 antibody, SF3b49 antibody, SF3B4 antibody, pre-mRNA-splicing factor SF3b 49 kDa subunit antibody, pre-mRNA splicing factor SF3b 49 kDa subunit antibody, SF3b50 antibody, spliceosome-associated protein 49 antibody, splicing factor 3B subunit 4 antibody, spliceosomal protein antibody, spliceosome-associated protein (U2 snRNP) antibody, SAP 49 antibody, "splicing factor 3b, subunit 4, 49kDa antibody"|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SF3B4. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (96%), Xenopus laevis (88%), Rhesus Monkey (100%), Bovine (100%)|