|Full Name||N-sulfoglucosamine sulfohydrolase|
|Product Description||Rabbit polyclonal antibody to SGSH (N-sulfoglucosamine sulfohydrolase)|
|Background||This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. [provided by RefSeq]|
|Synonyms||HSS antibody, MPS3A antibody, SFMD antibody, SGSH antibody, sulfoglucosamine sulfamidase antibody, sulphamidase antibody, mucopolysaccharidosis type IIIA antibody, heparan sulfate sulfatase antibody, N-sulphoglucosamine sulphohydrolase antibody, N-sulfoglucosamine sulfohydrolase antibody|
|Cellular Localization||Lysosome |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human SGSH. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Dog, Bovine|
|Predict Reactivity Note||Mouse (80%), Dog (81%), Bovine (80%)|