SHANK1 antibody [C3], C-term
|Applications||ICC/IF, IHC-Fr, IHC-P, WB|
Not tested in other applications.
|IHC (Frozen sections)||1:100-1:1000*
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||225 kDa (note)
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||SH3 and multiple ankyrin repeat domains 1|
|Product Description||Rabbit Polyclonal antibody to SHANK1 (SH3 and multiple ankyrin repeat domains 1)|
|Background||Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.|
|Synonyms||SPANK-1 antibody, SSTRIP antibody, synamon antibody, SHANK1 antibody, somatostatin receptor-interacting protein antibody, SH3 and multiple ankyrin repeat domains protein 1 antibody, SSTR-interacting protein antibody, SH3 and multiple ankyrin repeat domains 1 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SHANK1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (100%)|