|Full Name||serine hydroxymethyltransferase 1 (soluble)|
|Product Description||Rabbit Polyclonal antibody to SHMT1 (serine hydroxymethyltransferase 1 (soluble))|
|Background||This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]|
|Synonyms||CSHMT antibody, MGC15229 antibody, MGC24556 antibody, SHMT antibody, SHMT1 antibody, cytoplasmic serine hydroxymethyltransferase antibody, serine methylase antibody, glycine hydroxymethyltransferase antibody, "serine hydroxymethyltransferase, cytosolic antibody", 14 kDa protein antibody, serine hydroxymethyltransferase 1 (soluble) antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SHMT1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Rabbit, Sheep, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (94%), Rat (94%), Zebrafish (83%), Rabbit (94%), Sheep (95%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (95%)|