|Full Name||serine hydroxymethyltransferase 2 (mitochondrial)|
|Product Description||Rabbit Polyclonal antibody to SHMT2 (serine hydroxymethyltransferase 2 (mitochondrial))|
|Background||This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq]|
|Synonyms||GLYA antibody, SHMT antibody, SHMT2 antibody, GLY A+ antibody, serine hydroxymethylase antibody, serine hydroxymethyltransferase, mitochondrial antibody, serine methylase antibody, glycine hydroxymethyltransferase antibody, threonine aldolase antibody, glycine auxotroph A, human complement for hamster antibody, serine aldolase antibody, serine hydroxymethyltransferase 2 (mitochondrial) antibody|
|Cellular Localization||Mitochondrion |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human SHMT2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus Tropicalis, Rabbit, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (91%), Xenopus Tropicalis (80%), Rabbit (92%), Bovine (92%)|