|Full Name||signal-induced proliferation-associated 1|
|Product Description||Rabbit Polyclonal antibody to SIPA1 (signal-induced proliferation-associated 1)|
|Background||The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq]|
|Synonyms||MGC102688 antibody, MGC17037 antibody, SPA1 antibody, SIPA1 antibody, p130 SPA-1 antibody, sipa-1 antibody, GTPase-activating protein Spa-1 antibody, signal-induced proliferation-associated protein 1 antibody, signal-induced proliferation-associated gene 1 antibody, signal-induced proliferation-associated 1 antibody|
|Cellular Localization||Nucleus , Cytoplasm , perinuclear region , Endomembrane system; Peripheral membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SIPA1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (92%)|