|Full Name||sirtuin 3|
|Product Description||Rabbit Polyclonal antibody to SIRT3 (sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae))|
|Background||This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq]|
|Synonyms||SIR2L3 antibody, SIRT3 antibody, sir2-like 3 antibody, mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase antibody, sirtuin type 3 antibody, "silent mating type information regulation 2, S.cerevisiae, homolog 3 antibody", SIR2-like protein 3 antibody, "NAD-dependent deacetylase sirtuin-3, mitochondrial antibody", sirtuin 3 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SIRT3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Cat, Pig, Rabbit, Chicken, Bovine|
|Predict Reactivity Note||Mouse (82%), Cat (80%), Pig (85%), Rabbit (84%), Chicken (82%), Bovine (81%)|