|Full Name||sirtuin 5|
|Product Description||Rabbit Polyclonal antibody to SIRT5 (NAD-dependent deacetylase sirtuin-5)|
|Background||This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq]|
|Synonyms||FLJ36950 antibody, SIR2L5 antibody, SIRT5 antibody, sir2-like 5 antibody, SIR2-like protein 5 antibody, "silent mating type information regulation 2, S.cerevisiae, homolog 5 antibody", NAD-dependent deacetylase sirtuin-5 antibody, sirtuin type 5 antibody, sirtuin 5 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SIRT5. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Dog, Pig, Chicken, Bovine|
|Predict Reactivity Note||Mouse (90%), Rat (89%), Xenopus laevis (81%), Dog (90%), Pig (89%), Chicken (82%), Bovine (90%)|