|Full Name||S-phase kinase-associated protein 1|
|Product Description||Rabbit Polyclonal antibody to SKP1 (S-phase kinase-associated protein 1)|
|Background||This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq]|
|Synonyms||EMC19 antibody, MGC34403 antibody, OCP-II antibody, OCP2 antibody, SKP1A antibody, TCEB1L antibody, p19A antibody, SKP1 antibody, p19skp1 antibody, cyclin-A/CDK2-associated protein p19 antibody, cyclin A/CDK2-associated protein p19 antibody, SIII antibody, OCP-2 antibody, S-phase kinase-associated protein 1 antibody, RNA polymerase II elongation factor-like protein OCP2 antibody, organ of Corti protein 2 antibody, cyclin A/CDK2-associated p19 antibody, transcription elongation factor B antibody, organ of Corti protein II antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SKP1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Dog, Chicken, Sheep, Rhesus Monkey, Bovine, Guinea pig|
|Predict Reactivity Note||Rat (100%), Zebrafish (99%), Xenopus laevis (100%), Dog (100%), Chicken (100%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%), Guinea pig (100%)|