|Full Name||solute carrier family 4, sodium bicarbonate cotransporter, member 8|
|Product Description||Rabbit Polyclonal antibody to SLC4A8 (solute carrier family 4, sodium bicarbonate cotransporter, member 8)|
|Background||Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity. |
|Synonyms||DKFZp761B2318 antibody, FLJ46462 antibody, NBC3 antibody, NDCBE antibody, SLC4A8 antibody, electroneutral Na(+)-driven Cl-HCO3 exchanger antibody, electroneutral sodium bicarbonate exchanger 1 antibody, solute carrier family 4 member 8 antibody, k-NBC3 antibody, Na+-driven Cl-HCO3 exchanger antibody, "solute carrier family 4, sodium bicarbonate cotransporter, member 8 antibody"|
|Cellular Localization||Membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human SLC4A8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey|
|Predict Reactivity Note||Mouse (91%), Rat (91%), Rhesus Monkey (99%)|