Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Positive Controls||human Slug-transfected 293T cells , U87-MG , SK-N-SH , IMR32 , SK-N-AS , NT2D1|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||snail homolog 2 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to SLUG (snail homolog 2 (Drosophila))|
|Background||This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq]|
|Synonyms||WS2D Antibody, SLUGH1 Antibody, SNAI2 Antibody, snail homolog 2 (Drosophila) Antibody, SNAIL2 Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SLUG. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Dog, Pig, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (98%), Zebrafish (86%), Xenopus laevis (95%), Dog (100%), Pig (97%), Sheep (98%), Rhesus Monkey (100%), Bovine (99%)|