SMC3 antibody [C2C3], C-term
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||142 kDa (note)
|Positive Controls||HepG2 , NIH-3T3 , JC , BCL-1 , PC-12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||structural maintenance of chromosomes 3|
|Product Description||Rabbit Polyclonal antibody to SMC3 (structural maintenance of chromosomes protein 3)|
|Background||This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq]|
|Synonyms||BAM antibody, BMH antibody, CDLS3 antibody, CSPG6 antibody, HCAP antibody, SMC3L1 antibody, SMC3 antibody, SMC protein 3 antibody, SMC-3 antibody, structural maintenance of chromosomes protein 3 antibody, chromosome-associated polypeptide antibody, chondroitin sulfate proteoglycan 6 (bamacan) antibody, basement membrane-associated chondroitin proteoglycan antibody, structural maintenance of chromosomes 3 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human SMC3. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Zebrafish (95%), Xenopus laevis (98%), Chicken (99%), Bovine (92%)|