|Full Name||synaptosomal-associated protein, 25kDa|
|Product Description||Rabbit Polyclonal antibody to SNAP25 (synaptosomal-associated protein, 25kDa)|
|Background||Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq]|
|Synonyms||FLJ23079 antibody, RIC-4 antibody, RIC4 antibody, SEC9 antibody, SNAP antibody, SNAP-25 antibody, bA416N4.2 antibody, dJ1068F16.2 antibody, SNAP25 antibody, resistance to inhibitors of cholinesterase 4 homolog antibody, super protein antibody, SUP antibody, synaptosomal-associated protein 25 antibody, synaptosomal-associated protein, 25kDa antibody|
|Cellular Localization||Cytoplasm , perinuclear region (By similarity) , Cell membrane; Lipid-anchor , Cell junction , synapse , synaptosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SNAP25. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Xenopus laevis (94%), Chicken (94%), Rhesus Monkey (94%), Chimpanzee (94%), Bovine (94%)|