|Full Name||small nuclear ribonucleoprotein polypeptides B and B1|
|Product Description||Rabbit Polyclonal antibody to SNRPB (small nuclear ribonucleoprotein polypeptides B and B1)|
|Background||The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq]|
|Synonyms||COD antibody, SNRPB1 antibody, Sm-B/B' antibody, SmB/B' antibody, SmB/SmB' antibody, snRNP-B antibody, SNRPB antibody, small nuclear ribonucleoprotein polypeptide B antibody, small nuclear ribonucleoprotein-associated proteins B and B' antibody, small nuclear ribonucleoprotein polypeptides B and B' antibody, B polypeptide of Sm protein antibody, sm-B/Sm-B' antibody, Sm protein B/B' antibody, small nuclear ribonucleoprotein polypeptides B and B1 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SNRPB. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Xenopus laevis (81%), Chicken (96%), Rhesus Monkey (100%), Chimpanzee (96%), Bovine (99%)|