|Full Name||small nuclear ribonucleoprotein polypeptide N|
|Product Description||Rabbit Polyclonal antibody to SNRPN (small nuclear ribonucleoprotein polypeptide N)|
|Background||The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq]|
|Synonyms||DKFZp686C0927 antibody, DKFZp686M12165 antibody, DKFZp761I1912 antibody, DKFZp762N022 antibody, FLJ33569 antibody, FLJ36996 antibody, FLJ39265 antibody, HCERN3 antibody, MGC29886 antibody, PWCR antibody, RT-LI antibody, SM-D antibody, SMN antibody, SNRNP-N antibody, SNURF-SNRPN antibody, SNRPN antibody, sm protein D antibody, tissue-specific splicing protein antibody, small nuclear ribonucleoprotein-associated protein N antibody, tissue-specific-splicing protein antibody, SM protein N antibody, small nuclear ribonucleoprotein polypeptide N antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SNRPN. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Pig, Chimpanzee, Bovine|
|Predict Reactivity Note||Xenopus laevis (97%), Pig (100%), Chimpanzee (100%), Bovine (100%)|