|Full Name||sorting nexin 1|
|Product Description||Rabbit Polyclonal antibody to SNX1 (sorting nexin 1)|
|Background||This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq]|
|Synonyms||HsT17379 antibody, MGC8664 antibody, SNX1A antibody, Vps5 antibody, SNX1 antibody, sorting nexin-1 antibody, sorting nexin 1A antibody, sorting nexin 1 antibody|
|Cellular Localization||Endosome membrane; Peripheral membrane protein; Cytoplasmic side , Golgi apparatus , trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SNX1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Xenopus laevis (87%), Rhesus Monkey (100%), Bovine (98%)|