|Full Name||sorting nexin 1|
|Product Description||Goat polyclonal antibody to SNX1|
|Background||May be involved in several stages of intracellular trafficking. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with PtdIns(3,4,5)P3 and, with weaker affinity, with PtdIns(3,5)P2. |
|Synonyms||sorting nexin 1, Vps5, sorting nexin1, sorting nexin1A, SNX1, SNX1A, HsT17379, MGC8664, sorting nexin 1A|
|Specificity||This antibody is specific for SNX1.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Bovine|