|Full Name||sorting nexin 15|
|Product Description||Rabbit Polyclonal antibody to SNX15 (sorting nexin 15)|
|Background||This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms. [provided by RefSeq]|
|Synonyms||HSAF001435 antibody, SNX15 antibody, clone iota unknown protein antibody, sorting nexin-15 antibody, sorting nexin 15 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SNX15. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (92%), Bovine (94%)|