|Full Name||sorting nexin 6|
|Product Description||Rabbit Polyclonal antibody to SNX6 (sorting nexin 6)|
|Background||This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq]|
|Synonyms||MGC3157 antibody, MSTP010 antibody, TFAF2 antibody, SNX6 antibody, sorting nexin-6 antibody, TRAF4-associated factor 2 antibody, tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2 antibody, sorting nexin 6 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SNX6. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Zebrafish, Xenopus laevis, Pig, Chicken|
|Predict Reactivity Note||Human (100%), Mouse (99%), Rat (99%), Zebrafish (92%), Xenopus laevis (91%), Pig (99%), Chicken (97%)|