|Full Name||suppressor of cytokine signaling 1|
|Product Description||Rabbit Polyclonal antibody to SOCS1 (suppressor of cytokine signaling 1)|
|Background||This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq]|
|Synonyms||CIS1 antibody, CISH1 antibody, JAB antibody, SOCS-1 antibody, SSI-1 antibody, SSI1 antibody, TIP3 antibody, SOCS1 antibody, STAT induced SH3 protein 1 antibody, STAT-induced STAT inhibitor 1 antibody, cytokine-inducible SH2 protein 1 antibody, JAK-binding protein antibody, suppressor of cytokine signaling 1 antibody, TIP-3 antibody, JAK binding protein antibody, Tec-interacting protein 3 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SOCS1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (100%), Pig (100%)|