|Full Name||suppressor of cytokine signaling 3|
|Product Description||Rabbit Polyclonal antibody to SOCS3 (suppressor of cytokine signaling 3)|
|Background||This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq]|
|Synonyms||ATOD4 antibody, CIS3 antibody, Cish3 antibody, MGC71791 antibody, SOCS-3 antibody, SSI-3 antibody, SSI3 antibody, SOCS3 antibody, STAT-induced STAT inhibitor 3 antibody, cytokine-inducible SH2 protein 3 antibody, cytokine-induced SH2 protein 3 antibody, CIS-3 antibody, suppressor of cytokine signaling 3 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SOCS3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%)|