|Applications||ELISA, ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||16 kDa (note)
|Positive Controls||293T , HeLa , NT2D1 , SK-N-AS , IMR32 , SK-N-SH , U87-MG , mouse brain , Rat brain , *F79 , *F123|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||superoxide dismutase 1, soluble|
|Product Description||Rabbit Polyclonal antibody to SOD1 (superoxide dismutase 1, soluble)|
|Background||The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]|
|Synonyms||ALS antibody, ALS1 antibody, IPOA antibody, SOD antibody, homodimer antibody, SOD1 antibody, "superoxide dismutase, cystolic antibody", Cu/Zn superoxide dismutase antibody, indophenoloxidase A antibody, superoxide dismutase [Cu-Zn] antibody, "SOD, soluble antibody", "superoxide dismutase 1, soluble antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SOD1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Rabbit, Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Pig (80%), Rabbit (81%), Rhesus Monkey (91%), Chimpanzee (100%)|